There has been much debate regarding the 'double-effect' of sedatives and analgesics administered at the end-of-life, and the possibility that health professionals using these drugs are performing 'slow euthanasia.' On the one hand analgesics and sedatives can do much to relieve suffering in the terminally ill. On the other hand, they can hasten death. According to a standard view, the administration of analgesics and sedatives amounts to euthanasia when the drugs are given with an intention to hasten death. In this (...) paper we report a small qualitative study based on interviews with 8 Australian general physicians regarding their understanding of intention in the context of questions about voluntary euthanasia, assisted suicide and particularly the use of analgesic and sedative infusions (including the possibility of voluntary or non-voluntary 'slow euthanasia'). We found a striking ambiguity and uncertainty regarding intentions amongst doctors interviewed. Some were explicit in describing a 'grey' area between palliation and euthanasia, or a continuum between the two. Not one of the respondents was consistent in distinguishing between a foreseen death and an intended death. A major theme was that 'slow euthanasia' may be more psychologically acceptable to doctors than active voluntary euthanasia by bolus injection, partly because the former would usually only result in a small loss of 'time' for patients already very close to death, but also because of the desirable ambiguities surrounding causation and intention when an infusion of analgesics and sedatives is used. The empirical and philosophical implications of these findings are discussed. (shrink)

The multiplicity of deubiquitinating enzymes (DUBs) encoded by vertebrate genomes is partly attributable to whole genome duplication events that occurred early in chordate evolution. By surveying the literature for the largest family of DUBs (the ubiquitin-specific proteases), extensive functional redundancy for duplicated genes has been confirmed as opposed to singletons. Dramatically conflicting results have been reported for loss of function studies conducted through RNA interference as opposed to inactivating mutations, but the contradictory findings can be reconciled by a recently proposed (...) compensatory mechanism involving nonsense-mediated RNA degradation. Duplicated genes are often inactivated to become pseudogenes, and it is proposed that such is the fate of the USP15 gene of zebrafish, a commonly used model system. As it is reviewed here, these observations have implications not only for the interpretation of model system phenotypes but also for therapeutic interventions designed to target DUBs. (shrink)

St Anselm (1033-1109) devised an ontological “proof” of the existence of God based on the impossibility of conceiving of God's non-existence. This famous argument inspired a much less-widely known atheistic ontological “proof” of God's non-existence by Melbourne philosopher Douglas Gasking (1911-1994). Juxtaposing Gasking’s argument for the non-existence of God with Anselm’s “proof” brings the basic defect of Anselm’s argument into sharp relief.

The Long Fifteenth Century is intended as a companion volume to Douglas Gray's ground-breaking Oxford Book of Late Medieval Verse and Prose and incorporates a bibliography of his published writings. Gray's anthology revolutionized critical appreciation of English and Scottish literature of the `long fifteenth century' from the death of Chaucer to the Reformation, but the literature of the period as a whole remains much under-read, undervalued, and under-studied. The contributors to this volume, all leading scholars in the (...) field, bring to the fore the power of underrated writers, restore to the period writings often attributed to other centuries, open up new possibilities in neglected genres, offer radical rereadings of some more familiar works, and demonstrate how closely the literature of the period is bound up with political and social conditions. Written in honour of Douglas Gray, to mark his long and distinguished tenure of the J.R.R. Tolkein Professorship of English Literature and Language at Oxford university, the 15 essays in this volume portray the long fifteenth century as a major period of literature in its own right. They provide a comprehensive survey of fifteenth-century literature in print, from the morality play to the ballad, verse forms to prose romances, including Chaucer, Lydgate, Skelton, and Hoccleve, along with essays on the Middle French Poets and Scottish writings of the period. (shrink)

Context can determine whether a given gene acts as an oncogene or a tumor suppressor. Deubiquitinating enzymes (DUBs) regulate the stability of many components of the pathways dictating cell fate so it would be expected that alterations in the levels or activity of these enzymes may have oncogenic or tumor suppressive consequences. In the current review we survey publications reporting that genes encoding DUBs are oncogenes or tumor suppressors. For many DUBs both claims have been made. For such “double agents,” (...) the effects of gain or loss of function will depend on the overall status of a complex of molecular signaling networks subject to extensive crosstalk. As the TGF‐β paradox makes clear context is critical in cell fate decisions, and the disconnect between experimental findings and patient survival outcomes can in part be attributed to disparities between culture conditions and the microenvironment in vivo. Convincing claims for oncogene or tumor suppressor roles require the documentation of gene alterations in patient samples; survival curves are alone inadequate. (shrink)

The idea of forgiveness is omnipresent in the transitional justice literature, yet this body of work, taken as a whole, is marked by conceptual, terminological and argumentative imprecision. Equivocation is common, glossing moral, theological, therapeutic and legal considerations, while arguments proceed from political, apolitical and even antipolitical premises. With forgiveness as a praxis linked to reconciliation processes in at least ten countries, concerns have grown over its negative implications for the relationship between the state and victims of state-authored injustices. Many (...) of these debates reference Hannah Arendt. Drawing from a range of Arendt’s published and unpublished work, this article challenges the academic claim that forgiveness has no place in the politics of reconciliation. Through this ‘returning to the source’, it presents a promising mode of thinking about political forgiveness in contemporary Settler-colonial states. (shrink)

The nature/nurture debate is not dead. Dichotomous views of development still underlie many fundamental debates in the biological and social sciences. Developmental systems theory offers a new conceptual framework with which to resolve such debates. DST views ontogeny as contingent cycles of interaction among a varied set of developmental resources, no one of which controls the process. These factors include DNA, cellular and organismic structure, and social and ecological interactions. DST has excited interest from a wide range of researchers, from (...) molecular biologists to anthropologists, because of its ability to integrate evolutionary theory and other disciplines without falling into traditional oppositions. The book provides historical background to DST, recent theoretical findings on the mechanisms of heredity, applications of the DST framework to behavioral development, implications of DST for the philosophy of biology, and critical reactions to DST. (shrink)

Turning his back on neoliberalism, voicing 'the end of history' and the unstoppable spread of liberal values across the globe, Gray's was a lone voice of scepticism. The thinking he criticised would lead to the invasion of Iraq. Today, its folly might seem obvious, but Gray has been trying to warn us for years.

In her paper Expelled Again from Eden: Facing Difference through Connection, delivered in Plymouth in 1998, Mary Grey said the story of the Garden of Eden was a dilemma for Feminist Theologians. This because it both bears responsibility for the Fall of relationship between God and Man and the misogyny that has ensued through the ages but also underpinning the desire to return to a supposed golden age of matriarchy with the re-emergence of the Goddess and a related ecological and (...) egalitarian epoch of harmony. Grey makes a connection between the Lost Garden myth and the second wave feminist ideal of global sisterhood of the 1960s. Reflecting on her paper and updating it later, Grey concluded she still felt the challenge of years ago: the sense of rightness of connection and mutuality, yet the crucial need to embrace difference. (shrink)

Isaiah Berlin was the greatest intellectual historian of the twentieth century. But his work also made an original and important contribution to moral and political philosophy and to liberal theory. In 1921, at the age of eleven, Isaiah Berlin arrived in England from Riga, Latvia. By the time he was thirty he was at the heart of British intellectual life. He has remained its commanding presence ever since, and few would dispute that he was one of Britain's greatest thinkers. His (...) reputation extends worldwide--as a great conversationalist, intellectual historian, and man of letters. He has been called the century's most inspired reader. Yet Berlin's contributions to thought--in particular to moral and political philosophy, and to liberal theory--are little understood, and surprisingly neglected by the academic world. In this book, they are shown to be animated by a single, powerful, subversive idea: value-pluralism which affirms the reality of a deep conflict between ultimate human values that reason cannot resolve. Though bracingly clear-headed, humane and realist, Berlin's value-pluralism runs against the dominant Western traditions, secular and religious, which avow an ultimate harmony of values. It supports a highly distinctive restatement of liberalism in Berlin's work--an agnostic liberalism, which is founded not on rational choice but on the radical choices we make when faced with intractable dilemmas. It is this new statement of liberalism, the central subject of John Gray's lively and lucid book, which gives the liberal intellectual tradition a new lease on life, a new source of life, and which comprises Berlin's central and enduring legacy. In a new introduction, Gray argues that, in a world in which human freedom has spread more slowly than democracy, Berlin's account of liberty and basic decency is more instructive and useful than ever. (shrink)

We offer an interpretation of the mental files framework that eliminates the metaphor of files, information being contained in files, etc. The guiding question is whether, once we move beyond the metaphors, there is any theoretical role for files. We claim not. We replace the file-metaphor with two theses: the semantic thesis that there are irreducibly relational representational facts (viz. facts about the coordination of representations); and the metasemantic thesis that processes tied to information-relations ground those facts. In its canonical (...) statement, the ‘file’-theory makes reference to a certain kind of relational representational feature, and a certain kind of mental activity. Mental files need not come into it. In short, we posit mental filing without mental files. Our interpretation avoids awkward problems that arise on the standard interpretation and clarifies the explanatory commitments of the theory. (shrink)

_Liberalisms_, a work first published in 1989, provides a coherent and comprehensive analytical guide to liberal thinking over the past century and considers the dominance of liberal thought in Anglo-American political philosophy over the past 20 years. John Gray assesses the work of all the major liberal political philosophers including J. S. Mill, Herbert Spencer, Karl Popper, F. A Hayek, John Rawls and Robert Nozick, and explores their mutual connections and differences.

Mill on Liberty was first published in 1983 and has become a classic of Mill commentary. The second edition reproduces the text of the first in full, and in paperback for the first time. To this, John Gray adds an extensive postscript which defends the interpretation of Mill set out in the first edition, but develops radical criticisms of the substance of Millian and other liberalism. The new edition is intended as a contribution to the current debate about the (...) foundations of liberalism, and it looks closely at the recent seminal contributions to liberal thought by Raz, Feinberg, Rawls and Berlin. Central to its argument is Gray's contention that, like other liberalisms that ground themselves on an ideal of autonomy or individuality, Millian liberalism has a Eurocentric bias that cannot be given rational justification. Gray addresses the question of whether any form of liberal theory, can, in fact, avoid the bias, and concludes that it cannot. This book will be indispensable both to those familiar with On Liberty and to those coming to it for the first time. In addition, the book will also be of great interest to moral and political theorists, to students of law and jurisprudence and to intellectual historians. (shrink)

The ongoing explosion of interest in artificial intelligence is fueled in part by recently developed techniques in machine learning. Those techniques allow automated systems to process huge amounts of data, utilizing mathematical methods that depart from traditional statistical approaches, and resulting in impressive advancements in our ability to make predictions and uncover correlations across a host of interesting domains. But as is now widely discussed, the way that those systems arrive at their outputs is often opaque, even to the experts (...) who design and deploy them. Is it morally problematic to make use of opaque automated methods when making high-stakes decisions, like whether to issue a loan to an applicant, or whether to approve a parole request? Many scholars answer in the affirmative. However, there is no widely accepted explanation for why transparent systems are morally preferable to opaque systems. We argue that the use of automated decision-making systems sometimes violates duties of consideration that are owed by decision-makers to decision-subjects, duties that are both epistemic and practical in character. Violations of that kind generate a weighty consideration against the use of opaque decision systems. In the course of defending our approach, we show that it is able to address three major challenges sometimes leveled against attempts to defend the moral import of transparency in automated decision-making. (shrink)

Russellians, Relationists, and Fregeans disagree about the nature of propositional-attitude content. We articulate a framework to characterize and evaluate this disagreement. The framework involves two claims: i) that we should individuate attitude content in whatever way fits best with the explanations that characteristically appeal to it, and ii) that we can understand those explanations by analogy with other ‘higher-level’ explanations. Using the framework, we argue for an under-appreciated form of Russellianism. Along the way we demonstrate that being more explicit about (...) the framework in which debates about attitude content take place allows us to more precisely characterize the space of possible positions and the dialectic between them. (shrink)

"... chronicles the story of U.G. Krishnamurti, the Cosmic Naxalite, from his troubled childhood to his disillusionment with many of the leading spiritual teachers of the twentieth century and his catastrophic personal life. In 1967, UG underwent a series of biological mutations that left him in the 'natural state'--functioning without the interference of thought. With no fixed address, no followers and no organization, UG spent the next thirty years travelling the world with an uncompromising message: that 'mind is a myth' (...) and dthe human condition should be demystified and de-psyhologized and viewed in purely physiological terms."--Cover. (shrink)

Epicurus famously argued that death is never a harm to the one who dies, because there is no time at which the decedent is worse off. While the decedent is still alive death isn't a harm; but after death there is no one to be harmed. Life is death-excluding, and death is harm-excluding. When then can the decedent be worse off? Either: at no particular time; always; before death; at death; or, after death. In an earlier paper ('Epicurus and the (...) harm of Death') I argued that decedents may suffer posthumous harm. Here I answer objections to the posthumous harm proposal, and provide further clarification of this position. (shrink)

RESUMEN Se realizó un estudio descriptivo transversal cuanti-cualitativo, en función de la caracterización sicológica de los adolescentes con ideación suicida, atendidos en la consulta de Sicología del Centro Comunitario de Salud Mental “Joaquín de Agüero” del área de salud Pirre, Finlay y Norte en la provincia de Camagüey, en el período comprendido desde enero hasta diciembre de 2016. Por ello el objetivo del presente trabajo está dirigido a exponer los principales resultados del proceso de investigación al que se alude. Se (...) operó con un universo de 16 adolescentes. Se utilizó un muestreo intencional puro con criterios de inclusión y exclusión, la muestra quedó conformada por 13. Se emplearon métodos de nivel teórico, empíricos:, Test funcionamiento familiar, Idaren, Ideren, Autoestima de Coopersmith) y métodos estadísticos. Predominó el grupo etario entre 13 a 15 años, sexo femenino, escolaridad secundaria y estado civil soltero. Prevalecieron las familias nucleares monoparentales y reensambladas. El poco tiempo a compartir con los hijos pobre comunicación y conflictos con los padres son factores de riesgo en el funcionamiento familiar. La autoestima se comportó a niveles bajo, con carencia afectiva, sentimientos de soledad, falta de apoyo y poca tolerancia a las frustraciones. Se constataron niveles altos de ansiedad como estado y rasgo, la depresión como estado alto y como rasgo bajo y se encontró dañada la tríada afectiva. ABSTRACT A descriptive transversal quantitative-qualitative study was carried out in order to do a psychological characterization of teenagers with suicidal ideation. They were treated in the psychology consultation of the Joaquin de Aguero Mental Health Community Center from the Pirre, Finlay and North policlinics health area in Camaguey province from January to December 2016. Therefore, this paper is aimed at showing the main results of the research process which is made reference to. Sixteen teenagers were selected as population. A pure intentional sampling with inclusion and exclusion criteria was used and the final sample was 13 teenagers. Different methods were used: theoretical, empirical ), Family functioning test, Idaren, Ideren, Coopersmith Self-esteem) and statistical methods. It prevailed an age bracket between 13 and 15-year-old high school single teens. It prevailed nuclear single-parent and rejoined families. The short time parents share with children as well as the poor communication and the conflicts between them are family functioning risk factors. Self-esteem levels were low, with affection deprivation, loneliness feelings, lack of support and little tolerance towards frustrations. High anxiety levels such as state and trait were confirmed, as well as high state and low trait. The affective triad was found to be damaged. (shrink)

The account of natural kinds as stable property clusters is premised on the possibility of separating the epistemic value of natural kinds from their underlying metaphysics. On that account, the co-instantiation of any sub-cluster of the properties associated with a given natural kind raises the probability of the co-instantiation of the rest, and this clustering of property instantiation is invariant under all relevant counterfactual perturbations. We argue that it is not possible to evaluate the stability of a cluster of properties (...) without taking stock of the metaphysical picture used to account for that stability. Thus, even on the stable property cluster account, the epistemic value of natural kinds remains partly grounded in their metaphysical status. (shrink)

From dogs to gods, the science of understanding mysterious minds--including your own. Nothing seems more real than the minds of other people. When you consider what your boss is thinking or whether your spouse is happy, you are admitting them into the "mind club." It's easy to assume other humans can think and feel, but what about a cow, a computer, a corporation? What kinds of mind do they have? Daniel M. Wegner and Kurt Gray are award-winning psychologists who (...) have discovered that minds--while incredibly important--are a matter of perception. Their research opens a trove of new findings, with insights into human behavior that are fascinating, frightening and funny. The Mind Club explains why we love some animals and eat others, why people debate the existence of God so intensely, how good people can be so cruel, and why robots make such poor lovers. By investigating the mind perception of extraordinary targets--animals, machines, comatose people, god--Wegner and Gray explain what it means to have a mind, and why it matters so much. Fusing cutting-edge research and personal anecdotes, The Mind Club explores the moral dimensions of mind perception with wit and compassion, revealing the surprisingly simple basis for what compels us to love and hate, to harm and to protect. (shrink)

How does conscious experience arise out of the functioning of the human brain? How is it related to the behaviour that it accompanies? How does the perceived world relate to the real world? Between them, these three questions constitute what is commonly known as the Hard Problem of consciousness. Despite vast knowledge of the relationship between brain and behaviour, and rapid advances in our knowledge of how brain activity correlates with conscious experience, the answers to all three questions remain controversial, (...) even mysterious. This important book analyses these core issues and reviews the evidence from both introspection and experiment. To many its conclusions will be surprising and even unsettling: * The entire perceived world is constructed by the brain. The relationship between the world we perceive and the underlying physical reality is not as close as we might think * Much of our behaviour is accomplished with little or no participation from conscious experience. * Our conscious experience of our behaviour lags the behaviour itself by around a fifth of a second - we become aware of what we do only after we have done it. * The lag in conscious experience applies also to the decision to act - we only become aware of our decisions after they have been formed. * The self is as much a creation of the brain as is the rest of the perceived world. Written by a leading scientist, this accessible and compelling analysis of how conscious experience relates to brain and behaviour will have major implications for our understanding of human nature. (shrink)

In A Theory of Justice, John Rawls’s first argument for the inherent stability of a well-ordered society seeks to establish that citizens of such a society would come to share the same or similar senses of justice. In his late work, Rawls significantly revised his second argument for stability, but he repeatedly pronounced himself satisfied with the first. However, the pluralism that so drastically reoriented Rawls’s mature theory also creates destabilizing forces absent in Theory. These destabilizing forces suggest that a (...) shared sense of justice among citizens will be more difficult to achieve. This paper examines Rawl’s late theory in detail to reconstruct how Rawls, despite his stated satisfaction, addressed the destabilizing effects of pluralism through revisions to his first argument for stability. It argues that in his late theory Rawls no longer claims that a well-ordered society could achieve inherent stability. Instead, a more fragile stability is achieved through a disciplined commitment to publ... (shrink)

In this book John Gray argues that we live in a time of endings for the ideologies that governed the modern period. The Enlightenment projects of universal emancipation animates all the political doctrines and movements that are central in contemporary western societies. Yet it does not reflect the reality of the plural world in which we live. The western cultural hegemony which the Enlightenment embodied is coming to a close. Western liberal societies are not precursors of a universal civilization, (...) but only one form of life among many in the late modern world. Our inherited stock of political ideas no longer tracks that world. The crisis of New Right thought is as profound as that of the Left. Green theorists and communitarian thinkers have not understood the deep diversity and intractable conflicts of contemporary societies. And postmodernists, whose thought is ruled by the dated utopias of the modern period, do not engage with the real conditions of the world's emerging postmodern societies. Late modern thought occurs in an interregnum between modern projects that are no longer credible and postmodern realities that many find intolerable. John Gray suggests that some Enlightenment hopes of progress must be extinguished if we are to learn to respect cultural diversity and accept ecological limits. Respect for the Earth and for other species and cultures means abandoning the utopian and arcadian projects that haunt modern thought. We should aim to moderate the impact of human activity on the Earth while alleviating the unavoidable evils of human life. Yet the hubris which treats the Earth as an instrument of human purposes, and which regards other cultures as approximations to a universal civilization, embodies ancient and powerful traditions. John Gray's aim is to question these traditions and thereby to prepare our thinking for a time of beginnings. (shrink)

In an increasingly complex world with increasingly powerful organisations it seems inevitable that society – or groups in society – would become anxious about whether these organisations could be encouraged to match that power with an appropriate responsibility. This is the function of accountability – to require individuals and organisations to present an account of those actions for which society holds them – or would wish to hold them – responsible. And the history of social accounting, at its most fundamental, (...) is a history of attempts to develop this accountability. It seems to me that the widespread and systematic practice of social and environmental accounting is a deeply essential element in any well‐functioning, complex democracy. The corollary is that the absence of such mechanisms raises fundamental questions about the nature of modern democracies. This article briefly outlines what I believe to be the three strands of social accounting. It then identifies a few of the lessons that we may be able to learn from current experience and, in particular, how social accounting is related to accountability, democracy and sustainability. The central issue of the tension between accountability and control is touched upon: I then illustrate how the stakeholder model can be used to help define the social account, and conclude with a few words on attestation. (shrink)

This study reconsiders the purported benefits of community found in Community Supported Agriculture (CSA). Using an online survey of members who belong to CSAs in New York, between November and December 2010, we assess members’ reasons for joining a CSA, and their perceptions of community within their CSA and beyond. A total of 565 CSA members responded to the survey. Results show an overwhelming majority of members joined their CSA for fresh, local, organic produce, while few respondents joined their CSA (...) to build community, meet like-minded individuals or share financial risk with farmers. Members reported that they do not derive a strong sense of community from either their CSA or other forms of community, yet they volunteered at their CSA and appear to be engaged in activities within their communities, though the frequency of the latter is unknown. These data suggest New York CSAs are oriented toward the instrumental and functional models, which emphasize the economic aspects of farming rather than collaborative models, which foster community (Feagan and Henderson 2009). (shrink)

A great philosopher will change the way you think about your life. For most of human history, religion provided a clear explanation of life and death. But in the late 19th and early 20th centuries new ideas -- from psychiatry to evolution to Communist -- seemed to suggest that our fate was now in our own hands. We would ourselves become God. This is the theme of a remarkable new book by one of the world's greatest lving philosophers. It is (...) a brilliant and frightening look at the problems and opportunities of a world coming to grips with humankind's now solitary, unaided place in the universe. Gray takes two major examples: the belief that the science-backed Communism of the new USSR could reshape the planet, and the belief among a group of Edwardian intellectuals -- popularized through mediums and automatic writing -- that there was a non-religious form of life after death. Gray presents an extraordinary cast of philosophers, journalists, politicians, charlatans and mass murderers, all of whom felt driven by a specifically scientific and modern world view. He raises a host of fascinating questions about what it means to be human. The implications of Gray's book will haunt its readers for the rest of their lives. (shrink)

Collected here in a single volume for the first time, On Liberty, Utilitarianism, Considerations on Representative Government, and The Subjection of Women show Mill applying his liberal utilitarian philosophy to a range of issues that remain vital today - issues of the nature of ethics, the scope and limits of individual liberty, the merits of and costs of democratic government, and the place of women in society. In his Introduction John Gray describes these essays as applications of Mill's doctrine (...) of the Art of Life, as set out in A System of Logic. Using the resources of recent revisionist scholarship, he shows Mill's work to be far richer and subtler than traditional interpretations allow. (shrink)

The framework of plateaus, dips, and leaps shines light on periods when individuals may be inventing new methods of skilled performance. We begin with a review of the role performance plateaus have played in experimental psychology, human–computer interaction, and cognitive science. We then reanalyze two classic studies of individual performance to show plateaus and dips which resulted in performance leaps. For a third study, we show how the statistical methods of Changepoint Analysis plus a few simple heuristics may direct our (...) focus to periods of performance change for individuals. For the researcher, dips become the marker of exploration where performance suffers as new methods are invented and tested. Leaps mark the implementation of a successful new method and an incremental jump above the path plotted by smooth and steady log–log performance increments. The methods developed during these dips and leaps are the key to surpassing one's teachers and acquiring extreme expertise. (shrink)

Philosophy of ecology has been slow to become established as an area of philosophical interest, but it is now receiving considerable attention. This area holds great promise for the advancement of both ecology and the philosophy of science. Insights from the philosophy of science can advance ecology in a number of ways. For example, philosophy can assist with the development of improved models of ecological hypothesis testing and theory choice. Philosophy can also help ecologists understand the role and limitations of (...) mathematical models in ecology. On the other side, philosophy of science will be advanced by having ecological case studies as part of the stock of examples. Ecological case studies can shed light on old philosophical topics as well as raise novel issues for the philosophy of science. For example, understanding theoretical terms such as “biodiversity” is important for scientific reasons, but such terms also carry political importance. Formulating appropriate definitions for such terms is thus not a purely scientific matter, and this may prompt a reevaluation of philosophical accounts of defining theoretical terms. We consider some of the topics currently receiving attention in the philosophy of ecology and other topics in need of attention. Our aim is to prompt further exchange between ecology and philosophy of science and to help set the agenda for future work in the philosophy of ecology. The topics covered include: the role of mathematical models, environmental problem formulation, biodiversity, and environmental ethics. (shrink)

We draw attention to a series of implicit assumptions that have structured the debate about Frege’s Puzzle. Once these assumptions are made explicit, we rely on them to show that if one focuses exclusively on the issues raised by Frege cases, then one obtains a powerful consideration against a fine-grained conception of propositional-attitude content. In light of this consideration, a form of Russellianism about content becomes viable.

Some maladaptive thought processes are characterized by reflexive and habitual patterns of cognitive and emotional reactivity. We review theoretical and empirical work suggesting that mindfulness—a state of nonjudgmental awareness of the present moment—can facilitate the discontinuation of such automatic mental operations. We propose a framework that suggests a series of more specific mechanisms supporting the de-automatizing function of mindfulness. Four related but distinct elements of mindfulness (awareness, attention, focus on the present, and acceptance) can each contribute to de-automatization through subsequent (...) processes, including discontinuing automatic inference, enhancing cognitive control capacity, facilitating metacognitive insight, and preventing suppression or thought distortion. De-automatizing can, in turn, allow enhancement of adaptive self-control ability and increased well-being. (shrink)

The Developmental Systems approach to evolution is defended against the alternative extended replicator approach of Sterelny, Smith and Dickison (1996). A precise definition is provided of the spatial and temporal boundaries of the life-cycle that DST claims is the unit of evolution. Pacé Sterelny et al., the extended replicator theory is not a bulwark against excessive holism. Everything which DST claims is replicated in evolution can be shown to be an extended replicator on Sterelny et al.s definition. Reasons are given (...) for scepticism about the heuristic value claimed for the extended replicator concept. For every competitive, individualistic insight the replicator theorist has a cooperative, systematic blindspot. (shrink)

The paper engages Christopher Boorse’s Bio-Statistical Theory (BST). In its current form, BST runs into a significant challenge. For BST to account for its central tenet—that lower-level part-dysfunction is sufficient for higher-level pathology—it must provide criteria for how to decide which lower-level parts are the ones to be analyzed for health or pathology. As BST is a naturalistic theory, such choices must be based solely on naturalistic considerations. An argument is provided to show that, if BST is to be preserved, (...) such parthood choices are based on non-naturalistic considerations. We demonstrate that even when parthood choices are based on the best way to preserve BST, there are counterintuitive results which bring the central tenet of BST into question. (shrink)

A study of the political philosophy of the Russian born thinker explains how Isaiah Berlin came to reject ideological frameworks in favor of a pluralism that acknowledges the inevitable diversity of human values.

Technological developments have resulted in tremendous increases in the volume and diversity of the data and information that must be processed in the course of biomedical and clinical research and practice. Researchers are at the same time under ever greater pressure to share data and to take steps to ensure that data resources are interoperable. The use of ontologies to annotate data has proven successful in supporting these goals and in providing new possibilities for the automated processing of data and (...) information. In this chapter, we describe different types of vocabulary resources and emphasize those features of formal ontologies that make them most useful for computational applications. We describe current uses of ontologies and discuss future goals for ontology-based computing, focusing on its use in the field of infectious diseases. We review the largest and most widely used vocabulary resources relevant to the study of infectious diseases and conclude with a description of the Infectious Disease Ontology (IDO) suite of interoperable ontology modules that together cover the entire infectious disease domain. (shrink)

Essentialist facts, facts about what is essential to what, are explanatorily distinctive. They can often be appealed to in the course of metaphysically explaining some fact, while themselves serving as explanatory ends. In other words, when one arrives in the course of an explanation at an essentialist fact, it often seems like a legitimate place to stop. In certain contexts, they seem to provide a metaphysical backstop to making further explanatory demands. This paper defends the view that essentialist facts are (...) zero-grounded. Just as we can think of certain logical truths as truths derivable from the empty set of premises, we can think of the zero-grounded facts as the facts that obtain in virtue of the empty set of facts. On this picture, the essentialist facts are grounded, but they are grounded literally in nothing—grounded for free, automatically, and by default. -/- This view has been unpopular for many reasons, including concerns about the obscurity of the notion of zero-grounding. Concerns notwithstanding, I make the case that the zero-grounding view fares better than the alternative ground-theoretic accounts in making sense of certain explanatory roles essences plausibly play. After some preliminary remarks on how we should understand what an essentialist fact is as well as which ones serve as explanation stoppers, I introduce a widespread and attractive picture of what the essentialist facts are; they are domain fixing facts. I then argue that this feature of the essentialist facts well-positions them to serve as explanation stoppers. Afterwards, I argue that the zero-ground view best accommodates the domain-fixing conception of essence. (shrink)

This paper offers a critique of sustainability reporting and, in particular, a critique of the modern disconnect between the practice of sustainability reporting and what we consider to be the urgent issue of our era: sustaining the life-supporting ecological systems on which humanity and other species depend. Tracing the history of such reporting developments, we identify and isolate the concept of the ‘triple bottom line’ (TBL) as a core and dominant idea that continues to pervade business reporting, and business engagement (...) with sustainability. Incorporating an entity’s economic, environmental and social performance indicators into its management and reporting processes, we argue, has become synonymous with corporate sustainability; in the process, concern for ecology has become sidelined. Moreover, this process has become reinforced and institutionalised through SustainAbility’s biennial benchmarking reports, KPMG’s triennial surveys of practice, initiatives by the accountancy profession and, particularly, the Global Reporting Initiative (GRI)’s sustainability reporting guidelines. We argue that the TBL and the GRI are insufficient conditions for organizations contributing to the sustaining of the Earth’s ecology. Paradoxically, they may reinforce business-as-usual and greater levels of un-sustainability. (shrink)

Anger, disgust, elevation, sympathy, relief. If the subjective experience of each of these emotions is the same whether elicited by moral or nonmoral events, then what makes moral emotions unique? We suggest that the configuration of moral emotions is special—a configuration given by the underlying structure of morality. Research suggests that people divide the moral world along the two dimensions of valence (help/harm) and moral type (agent/patient). The intersection of these two dimensions gives four moral exemplars—heroes, villains, victims and beneficiaries—each (...) of which elicits unique emotions. For example, victims (harm/patient) elicit sympathy and sadness. Dividing moral emotions into these four quadrants provides predictions about which emotions reinforce, oppose and complement each other. (shrink)

Value-pluralism is commonly held to support liberal political morality. This is argued by John Rawls and his school and, more instructively, by Isaiah Berlin and Joseph Raz. Against this common view it is argued that a strong version of value-pluralism and liberalism are incompatible doctrines. Some varieties of ethical pluralism are distinguished, and the claim of value-incommensurability made by strong pluralism is elucidated. The argument that liberal political morality consists of principles of right that are unaffected by the truth of (...) strong pluralism is examined and rejected. Strong pluralism is understood as the view that some goods and bads are rationally incommensurable. It is argued that if strong value-pluralism is true, then liberal political morality cannot be defended. Neither negative liberty nor individual autonomy can have general priority if it is true that the central goods specified by liberal political morality are incommensurables. This difficulty is not avoided by liberal theories that do not demand the maximization of a single value such as liberty. If strong pluralism is true, then liberal institutions are not a standard of legitimacy by reference to which all regimes are to be assessed. They are merely one variety of modus vivendi . Liberal institutions have no universal legitimacy. Yet liberal cultures are partly constituted by a belief in the universal authority of the principles which inform their practices and institutions. This belief strong pluralism subverts. Value-pluralism and liberalism are rival doctrines. The political implication of strong pluralism is not liberalism but modus vivendi . Sometimes modus vivendi is best fostered by liberal institutions. Sometimes it is best fostered by non-liberal institutions. Where the latter is true, liberals and pluralists part company. (shrink)

The 'non-sensory' feelings of familiarity, rightness and tip-of-the-tongue postulated in the target article all find a natural explanation within existing models, including Gray's comparator model, of the way in which top-down and bottom-up processing interact to select the contents of consciousness.

A 20th anniversary edition of the art classic that celebrates the intersection of creative expression and spirituality—from one of the greatest living artists of our time Twenty years after the original publication of The Mission of Art, Alex Grey’s inspirational message affirming art’s power for personal catharsis and spiritual awakening is stronger than ever. In this special anniversary edition, Grey—visionary painter, spiritual leader, and best-selling author—combines his extensive knowledge of art history with his own experiences in creating art at the (...) boundaries of consciousness. Grey examines the roles of conscience and intention in the creative process, including practical techniques and exercises useful in exploring the spiritual dimensions of art. Challenging and thought-provoking, The Mission of Art will be appreciated by everyone who has ever contemplated the deeper purpose of creative expression. (shrink)

According to many contemporary metaphysicians, we ought to theorize in terms of grounding because of its promise to explicate the idea of reality having a layered structure. However, a tension emerges when one combines the layered structure view with the view that higher-level facts are not reducible to lower-level facts. This tension emerges from two problems. The first problem arises from the fact that grounding explanations entail true universal generalizations. In order to satisfy this constraint, we will face serious pressure (...) to make sure the entities involved in the grounded facts are appropriately connected to the entities involved in the grounding facts, otherwise the generalizations associated with those grounding claims will come out false. However, ensuring the appropriate connections seemingly leaves no way for the non-reductivist to fully squeeze out reference to higher-level entities as we descend the levels of ground. This threatens the result that some higher-level facts must be taken as fundamental, which the non-reductivist cannot accept. -/- I argue that we can resolve the tension by taking the connections at issue to be essentially true. We can call this view essentialist non-reductivism. One significant upshot of the argument is that we can see not only that essentialist non-reductivism successfully resolves the tension, but that in principle no better solution could be offered. (shrink)

Research ethics guidelines grew out of several infamous episodes where research subjects were exploited. There is significant international synchronization of guidelines. However, indigenous groups in New Zealand, Canada and Australia have criticized these guidelines as being inadequate for research involving indigenous people and have developed guidelines from their own cultural perspectives. Whilst traditional research ethics guidelines place a lot of emphasis on informed consent, these indigenous guidelines put much greater emphasis on interdependence and trust. This article argues that traditional guidelines (...) are premised on relationships of equal power, and that often the researcher has more power that is not fully equalized by providing information. Where there is a relationship of unequal power, then focusing on interdependence and trust is more likely to achieve ethical safety. We illustrate this thesis by describing the detail of a research project looking at the use of interpreters, where we video-recorded live consultations and then interviewed the patient, interpreter and doctor. We conclude by suggesting that mainstream research ethics guidelines should pay more attention to the development of a trustworthy relationship between subject and researcher, and that, following the lead from clinical medicine, we should develop a culturally competent ethical framework for research on human subjects. (shrink)

Spelling out in detail what we do and do not know about phenomenological experience, this book denies the common view of consciousness as a central decision...

This book is perhaps the first to open a dialogue between the two disciplines.

On the one hand, we think that our conscious perceptions are tied to some stage of whatever processing stream we have. On the other hand, we think that our conscious experiences have to resemble the computational states that instantiate them. However, nothing in our alleged stream resembles our experienced perceptions. Hence, a conflict. The question is: How can we go from what we know about neurons, their connections, and firing patterns, to explaining what conscious perceptual experiences are like? No intuitive (...) answer seems plausible. Our perceptual experiences are complex and unified; however, brains divide their processing tasks into small chunks and segregate those smaller pieces across the gray matter. In this essay, I conjecture that what corresponds to our visual perceptions are higher order patterns of bifurcation in an attractor phase space. If I am correct, then the problem of the explanatory gap in philosophy, the binding problem in psychology, and the problem of perception in neuroscience disappear. If the traditional computational perspective is wrong, and sensory processing is not piece-meal, step-wise, and segregated, then there is no need for something in the head to tie things together. (shrink)